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Genotoxicity

Genotoxicity

Sia Analiz

Genotoxicity

Genotoxicity test; It can be done in vitro using bacteria and mammalian cells, which are used to detect damages such as DNA adhesions, DNA breaks, gene mutations, chromosomal abnormalities, clastogenicity and aneuploidy occurring in the cell nucleus, chromosome or DNA structure, as well as using in vivo test systems.

Genotoxicity testing in SIA Analysis Laboratories AMES mutation test (OECD 471), micronucleus test (OECD 487) in vitro chromosomal aberration test, whose protocols are determined by the OECD guidelines within the scope of the ISO 10993-3 standard, using cell culture and microbial biotechnology laboratories within the scope of the GLP declaration of conformity. (OECD 473) is carried out.

 

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