Six-Pack Tests

Acute Systemic Toxicity

Acute toxicity studies evaluate the adverse effects that may be caused by a test substance after oral, dermal, intraperitoneal, or inhaled administration of a substance in a single dose or multiple doses for less than 24 hours. Acute toxicity studies provide information on the hazardous properties of a test item and allow the classification of chemicals according to the Globally Harmonized System of Classification and Labeling of Chemicals.

Six-Pack Toxicology Studies

The battery of tests assessing acute systemic toxicity (respiratory, oral, dermal, eye) is often referred to as the “Six-Pack”.

Sia Analysis Laboratories offers “six-pack” toxicology tests consisting of in vivo acute toxicology testing along with in vitro toxicology studies designed to meet regulatory requirements for acute toxicity testing.

These tests provide information on health hazards that can result from short-term exposure to a test substance by different routes of administration. In this context, as SIA Analysis Laboratories, we perform the following tests according to the principles of GLP (Good Laboratory Practices);

• Acute Oral Toxicity Test
• Acute Dermal Toxicity Test
• Acute Inhalation Toxicity Test
• Acute Dermal Irritation/ Corrosion Test
• Acute Eye Irritation/ Corrosion Test
• Sensitization Test

Please contact us for more information.